Kanna (Sceletium tortuosum) is a plant that’s been used in South Africa for hundreds of years. It contains substances (e.g. Mesembrine and Mesembrenone) which offer depressant and anxiolytic effects. The drug also seems to enhance the effects of cannabis, particularly its euphoria.
Also known as, “Sceletium Tortuosum“ in botany, Kanna is one of the most commonly used traditional herbs that work wonders for mind-alteration. Its impact on the evolution of human consciousness is profound. Since it is naturally available, consumers conveniently enjoy its mood boosting and anxiety-reducing effects.
Conveniently enough, some of the most notorious stress relief ingredients are derived from all-natural herbs and other plants which are known to have minimal (if any) side effects. One of the most underrated of these herbs is known as Sceletium tortuosum, or simply Kanna. Let’s take a look at what this ingredient can bring to the table for those coping with stress.
There are few studies of effects of Sceletium tortuosum in human subjects. In an interesting fMRI study, acute administration of 25 mg of Zembrin, a proprietary preparation of Sceletium tortuosum, attenuated reactivity to fearful faces in the amygdala. Follow-up connectivity analysis on the emotion-matching task further showed that amygdala-hypothalamus coupling was also reduced. Those results were interpreted as reflecting an anxiolytic dampening of activity in threat circuitry of the human brain